| 发明名称 |
TISSUE-ENGINEERED BONE REPAIR USING CULTURED PERIOSTEAL CELLS |
| 摘要 |
Periosteal cells have been grown in cell culture and have been shown to have an osteoblastic phenotype, with production of osteocalcin and glycosaminoglycan. When seeded into polymeric implants, repair of critical size cranial defects was demonstrated and was confirmed by histology, biochemical assays, and radiodensitometry.
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| 申请公布号 |
WO9714783(A1) |
申请公布日期 |
1997.04.24 |
| 申请号 |
WO1996US16664 |
申请日期 |
1996.10.17 |
| 申请人 |
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATI |
发明人 |
BREITBART, ARNOLD, S.;GRANDE, DANIEL, A. |
| 分类号 |
A61K35/12;A61L27/38;C12N5/00;C12N5/077;(IPC1-7):C12N5/06;C12N5/08;A61L27/00 |
主分类号 |
A61K35/12 |
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