N-TERMINAL MODIFIED G-CSF AND CONSENSUS INF PREFERABLY MODIFIED BY ATTACHMENT OF A WATER SOLUBLE POLYMER EG PEG

摘要

Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.