发明名称 |
New 16-methyl substituted steroid derivatives of pregna-1,4-dien-3,20-dione, their preparation, their use in the preparation of 16-methylene substituted steroids and new intermediates therefor |
摘要 |
<p>The invention relates to the compounds (I): …<IMAGE>… where R is methyl or free or protected -CH2OH, R1 and R'1 are methyl; branched alkyl (5 to 8 carbon atoms), aryl (up to 10 carbon atoms), heteroaryl or benzyl, n and m are 0 or 1, R2 and R3 are hydrogen or R2 is fluorine and R3 is formyloxy or acetyloxy and the dotted lines symbolise a possible bond, to their preparation from a delta-16(17) compound, to their application to the preparation of 16-methylene derivatives and to new intermediates.</p> |
申请公布号 |
EP0520879(B1) |
申请公布日期 |
1997.04.23 |
申请号 |
EP19920401764 |
申请日期 |
1992.06.24 |
申请人 |
ROUSSEL UCLAF |
发明人 |
BOIVIN, JEAN;CHAUVET, CHRISTINE;ZARD, SAMIR |
分类号 |
A01K63/04;A01K63/06;C07J5/00;C07J7/00;C07J31/00;C07J41/00;(IPC1-7):C07J31/00 |
主分类号 |
A01K63/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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