发明名称 |
Cloning and sequencing of the gene which codes for a new pilinic subunit of bordella pertussis |
摘要 |
The cloning and sequencing of the gene which codes for a new pilinic subunit of Bordetella pertussis are described. The aminoacid sequence of the mature subunit, deduced from its necleotide sequence, is similar but not identical to that of the known pilins 2, 3 and 6. Polypeptides having the aminoacid sequence of the mature pilinic subunit or of regions thereof are particularly useful for the development of synthetic acellular vaccines against pertussis.
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申请公布号 |
US5622706(A) |
申请公布日期 |
1997.04.22 |
申请号 |
US19940334425 |
申请日期 |
1994.11.04 |
申请人 |
SCLAVO S.P.A.;ENIRICERCHE S.P.A. |
发明人 |
PEDRONI, PAOLA;RIBOLI, BARBARA;DE FERRA, FRANCESCA;GRANDI, GUIDO;TOMA, SALVATORE;ARICO, BEATRICE;RAPPUOLI, RINO |
分类号 |
C12N1/20;A61K38/00;A61K39/00;A61P31/04;A61P37/04;C07K14/00;C07K14/195;C07K14/235;C07K14/41;C12N1/19;C12N1/21;C12P21/02;C12R1/01;C12R1/19;(IPC1-7):A61K39/02;A61K39/10;C12N15/00 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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