Polyether-substituted porphyrin anti-tumor agents

摘要

Tumor-active or tumor-diagnostic substances having preferred accumulation in the tumor, which are characterized in that they have at least two phenolic hydroxyl and/or amino groups, at least one aliphatic amino group, or at least one phenolic hydroxyl and/or amino group and at least one aliphatic amino group and that these groups are substituted with polyethylene glycol chains whose polymerization degree n is 5 to 250 and whose terminal hydroxyl group is substituted by C1-C12 alkyl ester or ether, each of the substances being substituted by at least two such polyethylene glycol chains.