| 摘要 |
FIELD: medicine, more particularly preparation of antitumor drugs of 2nd and 3d generations. SUBSTANCE: oxalate-ion is added to platinum tetrachloroplatinate (II) solution, and mixture is treated successively with solutions of ammonia, isopropylamine and hydrochloric acid. Cis- dichloroaminoisopropylamino platinum (II) thus prepared contains no admixtures of cis-dichlorodiamino platinum (II), cis-dichlorodiisopropyl-amino platinum (II) and potassium chloride. Yield of the desired product is 47%. EFFECT: more efficient preparation process. |
