METHOD OF PREPARING CRYSTALLINE ANHYDROUS BENZYLPENICILLIN SULFOXIDE FORM

摘要

FIELD: chemical technology, antibiotics. SUBSTANCE: crystalline anhydrous form of benzylpenicillin sulfoxide is obtained by thermic treatment of benzylpenicillin sulfoxide hydrate or solvate with some organic solvents and exhibits high purity degree and increased stability. The obtained substance is a semiproduct for synthesis of cephalosporin antibiotics. EFFECT: improved method of preparing. 2 tbl