SULFO BENZ[e]INDOCYANINE FLUORESCENT DYES

摘要

The present invention is directed to fluorescent dyes and its valence tautomers of formula (I), wherein Q represents a conjugated moiety that increases the fluorescent quantum yield of the compound; R1 is a functionalized group of the formula -(CH2)jY, wherein Y is selected from the group consisting of SO3H, COOH, NH2, CHO, NCS, epoxy, phthalimido, and COOZ, wherein Z represents a leaving group; R2 is a functionalized group of the formula -(CH2)kY', wherein Y' is selected from the group consisting of SO3H, COOH, NH2, CHO, NCS, epoxy, phthalimido, and COOZ, wherein Z represents a leaving group; M<+> is a counterion selected from the group consisting of ammonium, alkali metal cations, and alkaline earth metal cations; n = 1 to 4; m = 1 to 4; j = 2 to 10; and k = 2 to 10.