An isolated and purified non-denatured transferrin receptor protein of a Moraxella strain, particularly M. catarrhalis, has an apparent molecular mass of about 80 to about 90 kDa, as determined by SDS-PAGE. The transferrin receptor protein or a fragment analog thereof is useful in diagnostic applications and immunogenic compositions, particularly for in vivo administration to a host to confer protection against disease caused by a strain of Moraxella.
申请公布号
WO9713785(A1)
申请公布日期
1997.04.17
申请号
WO1996CA00684
申请日期
1996.10.11
申请人
CONNAUGHT LABORATORIES LIMITED;YANG, YAN-PING;MYERS, LISA, E.;HARKNESS, ROBIN, E.;KLEIN, MICHEL, H.
发明人
YANG, YAN-PING;MYERS, LISA, E.;HARKNESS, ROBIN, E.;KLEIN, MICHEL, H.