发明名称 |
Method for transferring genes to the heart using aav vectors |
摘要 |
The invention relates to the use of adeno-associated virus vectors for the transfer of genes to the heart and vasculature. The vector preferably contains a gene encoding a protein which improves heart and vascular function during heart failure. In a specific embodiment, the vector is introduced into the heart and vasculature via a catheter, with the aid of fluoroscopy. The method and vectors for use therein provide for safe and stable gene expression of the transferred genes. |
申请公布号 |
AU7246796(A) |
申请公布日期 |
1997.04.17 |
申请号 |
AU19960072467 |
申请日期 |
1996.09.26 |
申请人 |
THE ROCKEFELLER UNIVERSITY;MARTIN J. KAPLITT;EDWARD B. DIETHRICH |
发明人 |
MARTIN J. KAPLITT;EDWARD B. DIETHRICH;MICHAEL G KAPLITT |
分类号 |
C12N15/09;A61K31/00;A61K35/76;A61K48/00;A61P7/00;A61P7/02;A61P7/04;A61P9/00;A61P43/00;C12N15/864 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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