发明名称 PYRIMIDIN DERIVATIVES
摘要 The invention is concerned with compounds of general formula (I), wherein R<1> and R<2> each individually signify lower-alkyl or amino, A signifies A<1>, A<2>, A<3>, A<4>, A<5>, A<6> or A<7>; B signifies hydrogen in A<4>, A<5> and A<6>; (i) in A<1>-A<6>; lower-alkoxy in A<4>-A<6>; and lower alkyl, styryl, phenylethynyl or benzoyloxy-lower-alkyl in A<1> and A<2>; n signifies 0-2; m, p signify 0, 1 and R<3>, R<4>, R<5> and R<6> each independently signify hydrogen, halogen, lower-alkyl, trifluoromethyl, lower-alkoxy or nitro, and pharmaceutically acceptable acid addition salts thereof. These compounds can be used in the control or prevention of illnesses which are caused by disorders of the dopamine system. Psychotic illnesses such as e.g. schizophrenia belong to these.
申请公布号 WO9713759(A1) 申请公布日期 1997.04.17
申请号 WO1996EP04331 申请日期 1996.10.04
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GODEL, THIERRY;RIEMER, CLAUS;EDENHOFER, ALBRECHT
分类号 A61K31/505;A61P25/18;C07D239/26;C07D239/42;C07D239/47;C07D239/48;C07D401/06;(IPC1-7):C07D239/42 主分类号 A61K31/505
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