| 发明名称 |
METHODS OF INHIBITING PLASMINOGEN ACTIVATOR INHIBITOR 1 |
| 摘要 |
A method of inhibiting plasminogen activator inhibitor 1 comprising administering to a human in need thereof an effective amount of a compound having formula (I), wherein R<1> and R<3> are independently hydrogen, -CH3, (a) or (b), wherein Ar is optionally s ubstituted phenyl; R<2> is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt or solvate thereof.
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| 申请公布号 |
WO9713511(A1) |
申请公布日期 |
1997.04.17 |
| 申请号 |
WO1996US16059 |
申请日期 |
1996.10.07 |
| 申请人 |
ELI LILLY AND COMPANY;BERG, DAVID, T.;GRINNELL, BRIAN, W.;RICHARDSON, MARK, A. |
发明人 |
BERG, DAVID, T.;GRINNELL, BRIAN, W.;RICHARDSON, MARK, A. |
| 分类号 |
A61K31/38;A61K31/00;A61K31/381;A61K31/40;A61K31/4025;A61K31/445;A61K31/4465;A61K31/4523;A61K31/4535;A61K31/55;A61P5/36;A61P7/00;A61P7/02;A61P9/10;A61P31/00;A61P43/00;(IPC1-7):A61K31/40 |
主分类号 |
A61K31/38 |
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