| 发明名称 |
Replicative RNA-based amplification/detection systems |
| 摘要 |
This invention relates to the use of functional reporter molecules in the detection and measurement of targets in a sample. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target.
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| 申请公布号 |
US5620851(A) |
申请公布日期 |
1997.04.15 |
| 申请号 |
US19940323631 |
申请日期 |
1994.10.17 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
AXELROD, VLADIMIR D.;KRAMER, FRED R.;LIZARDI, PAUL M.;MILLS, DONALD R. |
| 分类号 |
C07H21/00;C12Q1/68;C12Q1/70;G01N33/532;(IPC1-7):C07H21/04;C12P19/34 |
主分类号 |
C07H21/00 |
| 代理机构 |
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