发明名称 |
FUSIONSPROTEINE VON MONOMEREN UND DIMEREN VON ANTIKÖRPERFRAGMENTEN |
摘要 |
PCT No. PCT/EP93/00082 Sec. 371 Date Jul. 22, 1994 Sec. 102(e) Date Jul. 22, 1994 PCT Filed Jan. 15, 1993 PCT Pub. No. WO93/15210 PCT Pub. Date Aug. 5, 1993The present invention describes a new class of antigen binding molecules which contain Fv-fragments of an antibody but do not use the constant antibody domains. They can also dimerize with other antibody fragment molecules or with non-antibody fragment molecules to form bi- or multifunctional antibody-fragment fusion proteins and so-called miniantibodies, respectively. The new fusion proteins can be used in the broad field of diagnostic and therapeutical medicine. |
申请公布号 |
AT151113(T) |
申请公布日期 |
1997.04.15 |
申请号 |
AT19930902206T |
申请日期 |
1993.01.15 |
申请人 |
MERCK PATENT GMBH |
发明人 |
PLUECKTHUN, ANDREAS;PACK, PETER |
分类号 |
C12N15/09;A61K38/00;A61K39/395;C07K14/39;C07K14/47;C07K16/00;C07K16/18;C07K16/46;C07K19/00;C12N15/13;C12N15/62;C12P21/02;C12P21/08;C12R1/09;G01N33/531 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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