发明名称 |
Chromatographic process for purification of insulin |
摘要 |
A process is described for obtaining insulin, which is virtually free from proteases and/or insulin acetylated at position A9, by chromatography in aqueous, buffered solvents which contain water-miscible organic solvents, on lipophilically modified silica gel, wherein the dissolving buffer contains acetone or acetonitrile.
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申请公布号 |
US5621073(A) |
申请公布日期 |
1997.04.15 |
申请号 |
US19950430273 |
申请日期 |
1995.04.28 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
DICKHARDT, RAINER;UNGER, BERNHARD;GRAEFE, CLAUDIA |
分类号 |
C07K1/14;C07K1/20;C07K14/575;C07K14/62;C12P21/00;C12P21/02;C12P21/06;(IPC1-7):A61K38/28 |
主分类号 |
C07K1/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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