摘要 |
PCT No. PCT/US94/03080 Sec. 371 Date Sep. 15, 1995 Sec. 102(e) Date Sep. 15, 1995 PCT Filed Mar. 22, 1994 PCT Pub. No. WO94/21614 PCT Pub. Date Sep. 29, 1994The present invention provides for the preparation of compounds,namely, 3-phenanthridinones and their derivatives and their unique ability to inhibit 5-alpha-reductase or their isozymes thereof in mammals enabling said compounds for treating hyperandrogenic conditions of acne, androgenic alopecia, male pattern baldness,female hirsutism,benign prostatic hyperplasia, prostatitis and prostatic cancer.
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