发明名称 SUBSTITUTED IMIDAZOLES HAVING ANTI-CANCER AND CYTOKINE INHIBITORY ACTIVITY
摘要 <p>Compounds represented by formula (I), are disclosed. <AR> represents an aromatic group containing 6-10 atoms; and (a) represents a 4 to 10 membered non-aromatic heterocycle containing at least one N atom, and optionally containing 1-2 additional N atoms and 0-1 O or S atom. A pharmaceutical composition is also included. Methods of treating cancer and cytokine mediated diseases are also included.</p>
申请公布号 WO9712876(A1) 申请公布日期 1997.04.10
申请号 WO1996US15880 申请日期 1996.10.02
申请人 MERCK & CO., INC;SELNICK, HAROLD, G.;CLAREMON, DAVID, A.;LIVERTON, NIGEL, J. 发明人 SELNICK, HAROLD, G.;CLAREMON, DAVID, A.;LIVERTON, NIGEL, J.
分类号 A61K31/00;A61K31/4427;A61K31/445;A61K31/4465;A61K31/4523;A61K31/4545;A61K31/495;A61K31/53;A61K31/535;A61P7/00;A61P17/00;A61P19/00;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P37/00;A61P37/02;A61P43/00;C07D233/76;C07D233/86;C07D233/88;C07D401/14;C07D405/14;C07D413/14;C07D417/14;(IPC1-7):C07D233/76 主分类号 A61K31/00
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