SUBSTITUTED IMIDAZOLES HAVING ANTI-CANCER AND CYTOKINE INHIBITORY ACTIVITY
摘要
<p>Compounds represented by formula (I), are disclosed. <AR> represents an aromatic group containing 6-10 atoms; and (a) represents a 4 to 10 membered non-aromatic heterocycle containing at least one N atom, and optionally containing 1-2 additional N atoms and 0-1 O or S atom. A pharmaceutical composition is also included. Methods of treating cancer and cytokine mediated diseases are also included.</p>
申请公布号
WO9712876(A1)
申请公布日期
1997.04.10
申请号
WO1996US15880
申请日期
1996.10.02
申请人
MERCK & CO., INC;SELNICK, HAROLD, G.;CLAREMON, DAVID, A.;LIVERTON, NIGEL, J.
发明人
SELNICK, HAROLD, G.;CLAREMON, DAVID, A.;LIVERTON, NIGEL, J.