METHOD AND COMPOSITION FOR TREATMENT OF OSTEOPOROSIS

摘要

The combination of the following active agents for treating osteoporosis: (a) a pharmacologically-acceptable alkalinizing potassium salt which produces hydroxyl ions and is thereby capable of reducing the acidity of tissue fluids or urine and which is selected from the group consisting of potassium bicarbonate and potassium salts of carboxylic acids which are metabolized to bicarbonate and thus alkalinize in vivo; and (b) a bisphosphonate which is effective as an antiresorptive agent for bone in the treatment of osteoporosis; the active ingredients being administered in amounts effective to treat osteoporosis without adversely affecting bone and acid-base homeostatis.