摘要 |
<p>The present invention provides an allenyl beta -lactam compound represented by the formula (1) <CHEM> wherein R<1> is a hydrogen atom, halogen atom, amino or protected amino, R<2> is a hydrogen atom, halogen atom, lower alkoxyl, lower acyl, lower alkyl, lower alkyl substituted with hydroxyl or protected hydroxyl, hydroxyl or protected hydroxyl, R<1> and R<2> representing =O when taken together, R<3> is a hydrogen atom or carboxylic acid protecting group, and X is the group -SO2R<4> or the group -SR<4>, R<4> being substituted or unsubstituted aryl or substituted or unsubstituted nitrogen-containing aromatic heterocyclic group.</p> |
申请人 |
OTSUKA KAGAKU K.K., OSAKA, JP |
发明人 |
TORII, SIGERU, AKAIWA-GUN, OKAYAMA-KEN, JP;TANAKA, HIDEO, OKAYAMA-SHI, OKAYAMA-KEN, JP;TANIGUCHI, MASATOSHI, C/O OTSUKA KAGAKU K.K., OSAKA-SHI, OSAKA-FU, JP;SASAOKA, MICHIO, C/O OTSUKA KAGAKU K.K., TOKUSHIMA-SHI, TOKUSHIMA-KEN, JP;SHIROI, TAKASHI, C/O OTSUKA KAGAKU K.K., TOKUSHIMA-SHI, TOKUSHIMA-KEN, JP;KAMEYAMA, YUTAKA, C/O OTSUKA KAGAKU K.K., TOKUSHIMA-SHI, TOKUSHIMA-KEN, JP |