| 发明名称 |
N<sub>2</sub>s<sub>2</sub>-type bi-functional nicotinamide chelating agents for radioactive isotopes |
| 摘要 |
The invention pertains to novel compounds of general formula (I) in which M stands for a radioisotope of Tc or Re, L stands for a ligand of general formula (II) in which R<1>, R<2>, R<3>, R<4>, R<5> and R<6> can have different meanings and stand for groups which are suitable both for the coordinate bonding of metal ions and for coupling to selectively self-concentrating compounds. The novel compounds are used to form complexes of technetium and rhenium and are used in medical diagnostics and therapy. |
| 申请公布号 |
AU1300597(A) |
申请公布日期 |
1997.04.09 |
| 申请号 |
AU19970013005 |
申请日期 |
1996.09.19 |
| 申请人 |
INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT |
发明人 |
LUDGER DINKELBORG;CHRISTOPH STEPHAN HILGER;WOLFGANG KRAMP;DR. JOHANNES PLATZEK;BERND RADUCHEL DR. |
| 分类号 |
A61K51/04;A61K51/08;A61K51/10;C07D213/82;C07F13/00;C07K5/083;C07K5/103;C07K7/14;C07K14/575 |
主分类号 |
A61K51/04 |
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