发明名称 |
NOVEL 4,6-DIARYLPYRIMIDINE DERIVATIVES AND SALTS THEREOF |
摘要 |
<p>Described are a 4,6-diarylpyrimidine derivative represented by the following formula (1): <CHEM> wherein R represents a heterocyclic ring which may be substituted by one to four lower alkyl groups or an amino group and Ar represents a phenyl, naphthyl or aromatic heterocyclic group which may have one to four substituents, and a salt thereof; a preparation process therefor; and a pharmaceutical containing it as an effective ingredient. It has excellent neovascular inhibitory action and is useful as a therapeutic agent for solid cancer, rheumatism, diabetic retinopathy or psoriasis.</p> |
申请公布号 |
EP0767170(A1) |
申请公布日期 |
1997.04.09 |
申请号 |
EP19960909366 |
申请日期 |
1996.04.12 |
申请人 |
TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
KONNO, YASUO;NOZAKI, KENJI;YAMADA, SHOZO;ASAO, TETSUJI;SUZUKI, TAKASHI;KIMURA, MASAYASU |
分类号 |
A61K31/505;A61P9/00;A61P17/06;A61P21/00;A61P27/02;A61P35/00;C07D239/42;C07D401/04;C07D403/12;C07D417/04;C07D521/00;C07F9/6512;(IPC1-7):C07D239/42;C07D401/12 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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