发明名称 |
QUINOLONE COMPOUNDS FOR THE TREATMENT OF DISORDERS CAUSED BY HELICOBACTER PYLORI |
摘要 |
This invention provides processes for producing quinolone compounds which comprise cultivating Amycolata sp. FERM BP-4785, and then isolating quinolone compounds from the fermentation broth. The compounds produced by these processes include compounds of formula (I) wherein R1 is H, R2 is (a) and R3 is CH3; R1 is CH3, R2 is (a) and R3 is CH3; or R1 is CH3, R2 is (b) and R3 is CH3; and the like. The present invention also relates to a pharmaceutical composition comprising the same, which is useful in the treatment of diseases, disorders and adverse conditions caused by Helicobacter pylori and is particularly useful in the treatment of gastroduodenal disorders, diseases and adverse conditions caused thereby.
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申请公布号 |
CA2229785(A1) |
申请公布日期 |
1997.04.10 |
申请号 |
CA19962229785 |
申请日期 |
1996.07.11 |
申请人 |
PFIZER INC. |
发明人 |
HUANG, LIANG H.;DEKKER, KOENRAAD A.;INAGAKI, TAISUKE;KOJIMA, YASUHIRO;KOJIMA, NAKAO;YAMAUCHI, YUJI |
分类号 |
A61K31/47;A61P1/04;A61P1/14;A61P31/04;C07D215/22;C07D215/233;C07D405/06;C12N1/14;C12N1/15;C12N1/20;C12P17/12;C12R1/01;(IPC1-7):C12N1/20 |
主分类号 |
A61K31/47 |
代理机构 |
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主权项 |
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地址 |
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