发明名称 Inhibited biological degradation of oligodeoxynucleotides
摘要 Disclosed is a method for inhibiting the biological degradation of a synthetic oligodeoxynucleotide or oligodeoxynucleotide analog placed into a cell or extracellular environment. Biological degradation is inhibited by the covalent attachment of a protection moiety, e.g., a fluorochrome label such as FITC or Texas red, to a modified base incorporated into the oligodeoxynucleotide or oligodeoxynucleotide analog.
申请公布号 AU7073096(A) 申请公布日期 1997.04.09
申请号 AU19960070730 申请日期 1996.09.16
申请人 UNIVERSITY OF MASSACHUSETTS 发明人 ROBERT H SINGER;JOAN C. POLITZ;KRISHAN L TANEJA
分类号 C07H21/00;C12Q1/68 主分类号 C07H21/00
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