发明名称 |
Hydrophobic amine polymer sequestrant and method of cholesterol depletion |
摘要 |
An amine polymer includes a substituent bound to an amine of the polymer. The substituent includes a quaternary amine-containing moiety having at least one hydrophobic moiety. A method for binding bile salts of bile acids in a mammal includes orally administering to the mammal a therapeutically-effective amount of the amine polymer.
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申请公布号 |
US5618530(A) |
申请公布日期 |
1997.04.08 |
申请号 |
US19950469659 |
申请日期 |
1995.06.06 |
申请人 |
GELTEX PHARMACEUTICALS, INC. |
发明人 |
MANDEVILLE, III, W. HARRY;HOLMES-FARLEY, STEPHEN R.;PETERSEN, JOHN S. |
分类号 |
A61K31/785;A61K31/787;A61P1/16;A61P3/06;A61P9/10;C07C211/63;C08F8/00;C08F8/02;C08F8/32;C08F8/44;C08F26/02;C08F220/34;C08F220/60;(IPC1-7):A61K31/785 |
主分类号 |
A61K31/785 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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