发明名称 |
Preparation of phytosphingosine derivative |
摘要 |
The invention concerns a process for preparing tetraacetylphytospingosine (TAPS) using F-60-10 mating type strain of Pichia ciferrii. Such strain is subjected to mutagenesis and the high TAPS producing strains are selected by a special procedure. These strains are grown in a fed batch mode on a non-fermentative carbon source at a temperature above 26 DEG C and the TAPS collected from the fermentation medium. Glycerol is a preferred carbon source and preferably L-serine is added to the culture medium.
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申请公布号 |
US5618706(A) |
申请公布日期 |
1997.04.08 |
申请号 |
US19950494850 |
申请日期 |
1995.06.26 |
申请人 |
QUEST INTERNATIONAL B.V. |
发明人 |
CASEY, JOHN;MAUME, KATHERINE A.;PETERS, ALFONS L. J.;VELOO, RUDOLF M. |
分类号 |
C12P13/02;C12N1/14;C12P13/00;C12R1/84;(IPC1-7):C12P13/00;C12N1/16 |
主分类号 |
C12P13/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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