Injizierbares Arzneimittel zum Schutz vor Gewebebeschädigung durch Ischemie

摘要

Disclosed is an ex vivo tissue perfusion composition for perfusing tissues and organs comprising: blood; a solution with an effective amount of an anticoagulant; and an effective amount of a surface-active copolymer of the following formula: HO(C2H4O)b(C3H6O)a(C2H4O)bH wherein a is an integer such that the hydrophobe represented by (C3H6O) has a molecular weight of approximately 950 to 4000, preferably from 1750 to 4000, and b is an integer such that the hydrophile portion represented by (C2H4O) constitutes from approximately 50% to 90% by weight of the compound and the use of said ex vivo tissue perfusion composition for perfusing tissues and organs for the manufacture of a medicament for the preservation of an ex vivo organ.