摘要 |
<p>Transdermal administration of certain indolone derivatives which are dopamine D2 agonists is described. The method involves treating an individual afflicted with Parkinson's disease by administering an indolone derivative, e.g., ropinirole base or a pharmaceutically acceptable ropinirole salt, through the skin or mucosal tissue, for a time period and at an administration rate effective to alleviate the symptoms of the disease. Pharmaceutical formulations and drug delivery systems for administering the drugs are provided as well.</p> |