摘要 |
The present invention provides a new immunosuppressant. An immunosuppressant containing as an active ingredient a compound represented by formula (I), wherein Y represents a nitrogen atom or C-G (G is an optionally esterified or amidated carboxyl group, an acyl group, an optionally protected hydroxyalkyl group, or a halogen atom); R is an optionally substituted hydrocarbon residue or an optionally substituted heterocyclic group; X is an oxygen atom or an optionally oxidized sulfur atom; n is 0 or 1, k is 0 or 1, G and R may bind together to form a ring; rings A and B may each have a substituent, or a pharmaceutically acceptable salt thereof. And a pharmaceutical composition which comprises a compound represented by the above formula (I) or a pharmaceutically acceptable salt thereof, and an immunosuppressant except for the compound of the above formula (I), and is useful as an immunosuppressant. |