发明名称 |
AMIDE TETRAZOLE ACAT INHIBITORS. |
摘要 |
<p>Pharmaceutically useful compounds having ACAT inhibitory activity of formula (I) wherein n is zero, one or two; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from 1 to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group, and R4 is a hydrocarbon group having from 1 to 20 carbon atoms.</p> |
申请公布号 |
GR3021942(T3) |
申请公布日期 |
1997.03.31 |
申请号 |
GR19960403360T |
申请日期 |
1996.12.06 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
O'BRIEN, PATRICK, MICHAEL;PICARD, JOSEPH, ARMAND;PURCHASE, CLAUDE FORSEY JR.;ROTH, BRUCE, DAVID;SLISKOVIC, DRAGO, ROBERT;WHITE, ANDREW, DAVID |
分类号 |
A61K31/41;A61K31/435;A61K31/495;A61P9/10;A61P43/00;C07D231/12;C07D233/54;C07D249/04;C07D257/04;C07D261/08;C07D271/06;C07D271/10;C07D277/22;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D471/04;(IPC1-7):C07D257/04 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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