发明名称 |
PREVENTING TISSUE ADHESION USING -i(IN SITU) MODIFICATION OF ALGINATE. |
摘要 |
<p>A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies the alginate in situ to an insoluble gel. This in situ modification provides a final product which can be compressed within the intra-articular space thus remaining localized. The modified material can have varied mechanical strengths and thus varied degradation times and can serve as a matrix for localizing and slowly releasing therapeutic agents. The modified material is biocompatible and biodegradable, thus requiring no reoperation for removal.</p> |
申请公布号 |
GR3022093(T3) |
申请公布日期 |
1997.03.31 |
申请号 |
GR19960403540T |
申请日期 |
1996.12.18 |
申请人 |
HOWMEDICA INC. |
发明人 |
ABERMAN, HAROLD M.;BARRY, JAMES J.;HIGHAM, PAUL A. |
分类号 |
A61K33/06;A61K31/715;A61L31/04;A61P43/00;(IPC1-7):A61K31/725;A61L31/00 |
主分类号 |
A61K33/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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