发明名称 Imidazoindolizine derivatives and process for preparation thereof
摘要 <p>An imidazoindolizine derivative of the formula [I]: <CHEM> wherein R<1> is lower alkyl, R<2> is hydrogen, cyano, lower alkyl, lower alkanoyl, lower alkoxycarbonyl, phenyl-lower alkoxycarbonyl, lower alkylsulfonyl, substituted or unsubstituted phenyl, arylcarbonyl, or 5- or 6-membered nitrogen-containing heteromonocyclic group-substituted carbonyl, Ring A is substituted or unsubstituted phenyl, and m is 0 or 1, or a pharmaceutically acceptable salt thereof, and process for preparation thereof, said imidazoindolizine derivatives and pharmaceutically acceptable salts thereof show excellent angiotensin II inhibitory activities and are useful in the prophylaxis or treatment of hypertension.</p>
申请公布号 GR3022106(T3) 申请公布日期 1997.03.31
申请号 GR19960403177T 申请日期 1996.12.19
申请人 TANABE SEIYAKU CO., LTD. 发明人 HONMA, YASUSHI;SEKINE, YASUO;NOMURA, SUMIHIRO;NAITO, KAZUAKI;NARITA, HIROSHI
分类号 A61K31/435;A61P9/12;A61P43/00;C07D471/04;C07D471/14;C07D487/04;(IPC1-7):C07D471/14 主分类号 A61K31/435
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