SUBSTITUTED BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENT OR DIAGNOSTIC AGENT, AND MEDICAMENT COMPRISING THEM

摘要

Substituted benzoylguanidines, a process for their preparation, their use as medicament or diagnostic agent, and medicament comprising them Compounds of the formula I <IMG> I in which the substituents have the meanings given in the description, and their pharmaceutically tolerated salts, are obtained by reaction with guanidine of a compound II <IMG> II in which R(1) to R(5) have the meaning given and L is a leaving group which can easily be replaced nucleophilically. Compounds I are outstanding cardiovascular therapeutics.