发明名称 Crystal of hydrate and process for preparation thereof
摘要 A novel dihydrate crystal of 3-Ä4-(8-fluoro-5,11-dihydrobenzÄbÜoxepinoÄ4,3-bÜpyridin-11-ylidene)pip eridinoÜpropionic acid providing high-intensity diffraction peaks at diffraction angles (2&thetas;) of about 4.2 DEG , 17.0 DEG , and 21.3 DEG in a powder X-ray diffraction profile; a medicament comprising said dihydrate crystal; and a process for preparing said dihydrate crystal which comprises the steps of treating a crystalline substance containing an anhydride crystal of the above compound with hydrous acetone, and subjecting the product to drying treatment and moistening treatment.
申请公布号 AU6754296(A) 申请公布日期 1997.03.27
申请号 AU19960067542 申请日期 1996.08.23
申请人 HOKURIKU SEIYAKU CO., LTD. 发明人 YASUO ITO;HIDEO KATO;SHINGO YASUDA;NORIYUKI KADO;NOBUHIKO IWASAKI;HIROYUKI NISHINO;MAKOTO TAKESHITA
分类号 C07D491/04;C07D491/044 主分类号 C07D491/04
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