METHOD OF PROTEIN C PRODUCTION INCREASE, METHOD OF INCREASE OF ITS MODIFICATION LEVEL

摘要

FIELD: biotechnology, genetic engineering. SUBSTANCE: invention relates to method of production of high levels of functional recombinant proteins in adenovirus-transformed mammalian cells. Method involves incubation of cells which are able to produce recombinant proteins at 38-39 C. Method ensures to increase the total protein expression level in some cellular lines and that of functional protein in the rest cellular lines. EFFECT: enhanced effectiveness of method.