| 摘要 |
<p>Novel cyclosporins having a high water-solubility, a high peroral absorbability and a reduced nephrotoxicity and a medicinal composition containing the same. The compounds include phosphates, salts thereof and solvates thereof of [phosphonothreonine2]cyclosporin A, [phosphono-4-hydroxynorvaline2]cyclosporin A, [phosphono-D-serine3]cyclosporin A, and [phosphonothreonine2, phosphono-D-serine3]cyclosporin A.</p> |
