发明名称 Bifunktionelle Nicotinamid-Chelatbildner vom Typ N¶2¶S¶2¶ für radioaktive Isotope
摘要 The invention pertains to novel compounds of general formula (I) in which M stands for a radioisotope of Tc or Re, L stands for a ligand of general formula (II) in which R<1>, R<2>, R<3>, R<4>, R<5> and R<6> can have different meanings and stand for groups which are suitable both for the coordinate bonding of metal ions and for coupling to selectively self-concentrating compounds. The novel compounds are used to form complexes of technetium and rhenium and are used in medical diagnostics and therapy.
申请公布号 DE19536783(A1) 申请公布日期 1997.03.27
申请号 DE19951036783 申请日期 1995.09.21
申请人 INSTITUT FUER DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAET BERLIN, 14050 BERLIN, DE 发明人 DINKELBORG, LUDGER, DR., 13583 BERLIN, DE;HILGER, CHRISTOPH STEPHAN, DR., 13353 BERLIN, DE;KRAMP, WOLFGANG, DR., 13503 BERLIN, DE;PLATZEK, JOHANNES, DR., 12621 BERLIN, DE;RADUECHEL, BERND, DR., 13465 BERLIN, DE
分类号 A61K51/04;A61K51/08;A61K51/10;C07D213/82;C07F13/00;C07K5/083;C07K5/103;C07K7/14;C07K14/575;(IPC1-7):C07K14/00;C07F19/00;C07K7/00;C07K9/00;C07K16/00;C07H21/00;G21H5/02;G01T1/164 主分类号 A61K51/04
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