发明名称 NOVEL HETEROCYCLIC COMPOUNDS
摘要 A compound of formula (I), wherein R<1> and R<2> independently are hydrogen, halogen, trifluoromethyl, hydroxy, C1-6-alkyl or C1-6-alkoxy; and R<3> is hydrogen or C1-3-alkyl; and A is C1-3-alkylene; and Y is ><u>C</u>H-CH2-, ><u>C</u>=CH-, ><u>C</u>H-O-, ><u>C</u>=N-, ><u>N</u>-CH2- wherein only the underscored atom participates in the ring system, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
申请公布号 WO9711071(A1) 申请公布日期 1997.03.27
申请号 WO1996DK00382 申请日期 1996.09.12
申请人 NOVO NORDISK A/S 发明人 HOHLWEG, ROLF;JOERGENSEN, TINE, KROGH;ANDERSEN, KNUD, ERIK;OLSEN, UFFE, BANG;MADSEN, PETER;POLIVKA, ZENDEK;KOENIGOVA, OTYLIE;MIKSIK, FRANTISEK;KOVANDOVA, MARTINA;SILHANKOVA, ALEXANDRA;SINDELAR, KAREL
分类号 C07D321/12;A61K31/335;A61K31/357;A61K31/4406;A61K31/55;A61P3/08;A61P25/00;A61P29/00;C07D273/00;C07D273/01;C07D405/06;C07D405/12;C07D413/06;(IPC1-7):C07D405/06;A61K31/455;A61K31/445;A61K31/40 主分类号 C07D321/12
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