| 发明名称 |
Amidinophenol derivatives |
| 摘要 |
Amidinophenol derivatives of the formula (I) <IMAGE> (I) wherein the various symbols are as defined herein; which have inhibitory activities on PLA2 and on various proteases such as trypsin, plasmin, thrombin, kallikrein, especially trypsin, and are useful for the prevention and/or the treatment of various inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis, severity in pancreatitis and multiple organ failure.
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| 申请公布号 |
US5614555(A) |
申请公布日期 |
1997.03.25 |
| 申请号 |
US19950464206 |
申请日期 |
1995.06.05 |
| 申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
NAKAI, HISAO;KAWAMURA, MASANORI;MIYAMOTO, TSUMORU |
| 分类号 |
C07D295/18;A61K31/235;A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61K31/495;A61P29/00;A61P37/08;A61P43/00;C07C257/18;C07C323/59;C07C323/62;C07C323/63;C07D205/04;C07D207/08;C07D207/16;C07D209/20;C07D223/04;C07D295/185;C07D295/192;(IPC1-7):A61K31/165;A61K31/24;C07C229/36;C07C271/18 |
主分类号 |
C07D295/18 |
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