发明名称 |
Process for preparing 1,3-dialkyl-5-hydroxyoxindoles and the ether derivatives thereof |
摘要 |
The invention is directed to a process for preparing a 1,3-dialkyl-5-hydroxyoxindole of formula 1: xy-( alpha -haloacyl)anilide of formula 2: <IMAGE> 2 wherein the substituents are as defined herein, in the presence of an anhydrous zinc halide to a temperature in the range from about 120 DEG C. to about 160 DEG C., and isolating the 1,3-dialkyl-5-hydroxyoxindole prepared.
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申请公布号 |
US5614637(A) |
申请公布日期 |
1997.03.25 |
申请号 |
US19950448222 |
申请日期 |
1995.05.23 |
申请人 |
BOEHRINGER INGELHEIM KG |
发明人 |
SOBOTTA, RAINER;SCHWARZ, RAINER;PSIORZ, MANFRED |
分类号 |
C07D209/34;(IPC1-7):C07D209/34 |
主分类号 |
C07D209/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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