Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract

摘要

A pharmaceutical preparation for oral administration comprising (a) a core containing a medicinal active ingredient, (b) a press-coated layer comprising a pH-independently water-soluble polymer, said layer being provided around the core and (c) a film comprising an enteric polymer, said film being provided around the press-coated layer. In the pharmaceutical preparation of the present invention, the medicinal active ingredient is not released during residence in the stomach and, after forwarded from the stomach, until reaching a targeted site in the intestine, and thereafter is quickly released, so that the medicinal active ingredient is efficiently delivered to the targeted site in the intestinal tract.