发明名称 |
Small molecule inhibitors of rotamase enzyme |
摘要 |
This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
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申请公布号 |
US5614547(A) |
申请公布日期 |
1997.03.25 |
申请号 |
US19950479436 |
申请日期 |
1995.06.07 |
申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
HAMILTON, GREGORY S.;STEINER, JOSEPH P. |
分类号 |
C12N9/99;A61K31/40;A61K31/401;A61K31/4025;A61K38/00;A61P21/00;A61P21/02;A61P25/00;A61P25/02;A61P25/16;A61P25/24;A61P25/28;A61P37/00;A61P43/00;C07B53/00;C07D207/16;C07D401/06;C07D405/06;C07D405/12;C07D407/04;C07D409/04;C07D409/12;C07D409/14;C07D417/04;C07D417/12;C07K5/078;(IPC1-7):C07D207/16 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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