发明名称 |
Ri fusion antigen recognized by antibodies associated with paraneoplastic opsoclonus and methods of use thereof |
摘要 |
An isolated nucleic acid sequence encoding Ri paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified Ri antigenic polypeptide and compositions containing the purified Ri antigenic polypeptide. Further provided by this invention is a antibody directed to an epitope on the Ri paraneoplastic antigenic polypeptide. Compositions containing this antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
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申请公布号 |
US5614371(A) |
申请公布日期 |
1997.03.25 |
申请号 |
US19940187793 |
申请日期 |
1994.01.26 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
POSNER, JEROME B.;DARNELL, ROBERT B.;FURNEAUX, HENRY M. |
分类号 |
A61K38/00;C07K14/47;C07K14/82;G01N33/574;(IPC1-7):G01N33/579;C07K19/00;C07K14/705 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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