| 摘要 |
A non-toxic oil-in-water or bicontinuous microemulsion as a vehicle for administration of one or more active compounds having a low solubility in water, which microemulsion contains: a polar phase containing water and optionally an agent for obtaining isotonic conditions, and one or more components (modifiers) for adjusting the polarity of the polar phase; a surfactant film modifier; a non-polar phase consisting of at least one pharmaceutically acceptable oil; and a mixture of a hydrophilic surfactant and a hydrophobic surfactant up to 15 % by weight of the total microemulsion, wherein the hydrophobic surfactant is chosen from a group consisting of lecithin, sphingolipids or galacto lipids.
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