发明名称 DOPAMINE RECEPTOR LIGANDS AND IMAGING AGENTS
摘要 Novel CNS dopamine D-1 receptors, such as the compound ( 1H-3-benzazepine-7-ol, are disclosed. These compounds are useful as imaging agents for D-1 receptors in the human brain and exhibit good brain retention and in vivo stability. The invention also extends to a process for preparing the novel compounds, and to novel intermediates useful in the preparation of the novel compounds.
申请公布号 CA2011738(C) 申请公布日期 1997.03.18
申请号 CA19902011738 申请日期 1990.03.08
申请人 TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (THE) 发明人 KUNG, HANK F.
分类号 A61K51/00;A61K51/04;C07D223/16;C07F3/14;C07F7/08;C07F7/10;C07F7/22;G01N33/50;(IPC1-7):C07D223/16;C07F3/12 主分类号 A61K51/00
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