发明名称 Certain diacyl hydrazine derivatives
摘要 The invention concerns acid derivatives of formula IR1-CON(R2)-N(R3)CO-X1-Q-X2-GIand pharmaceutically acceptable metabolically labile esters or amides thereof, and pharmaceutically acceptable salts thereof, in which R1, R2, R3, X1, Q, X2 and G have the meanings given in the specification. The invention also concerns processes for the preparation of the acid derivatives of formula I, pharmaceutical compositions containing them and their use as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa.
申请公布号 US5612373(A) 申请公布日期 1997.03.18
申请号 US19940266375 申请日期 1994.06.27
申请人 ZENECA LIMITED 发明人 BREWSTER, ANDREW G.;CAULKETT, PETER W. R.;FAULL, ALAN W.;PEARCE, ROBERT J.;SHUTE, RICHARD E.
分类号 C07D295/14;A61K31/195;A61K31/215;A61K31/445;A61K31/4465;A61P7/02;A61P9/08;A61P9/10;A61P25/04;A61P43/00;C07C243/38;C07C257/18;C07D211/34;C07D211/42;C07D211/46;C07D211/62;C07D295/20;C07D295/215;(IPC1-7):C07C243/38;C07C255/46;A61K31/165;A61K31/275 主分类号 C07D295/14
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