| 发明名称 |
Non-infectious foot-and-mouth disease viruses |
| 摘要 |
A safe, effective vaccine for the protection of susceptible animals against foot-and-mouth disease has been produced. The vaccine comprises a mutant virus from which the amino acid sequence Gly-Val-Arg-Gly-Asp-Phe (SEQ ID NO: 8) from the G-H loop of VP1 has been deleted and replaced with the amino acid sequence Asn-Pro. The mutant virus retains its antigenicity but is not infectious.
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| 申请公布号 |
US5612040(A) |
申请公布日期 |
1997.03.18 |
| 申请号 |
US19950418716 |
申请日期 |
1995.04.07 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE |
发明人 |
MASON, PETER W.;BAXT, BARRY;REIDER, ELIZABETH;BERINSTEIN, ANALIA;KANG, ANGRAY S. |
| 分类号 |
A61K39/00;C07K14/09;C07K14/705;(IPC1-7):A61K39/135;C12N7/04;C12N7/06;C07H21/02 |
主分类号 |
A61K39/00 |
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