PREPARATION OF RIBOFLAVIN-5'-PHOSPHATE (5'-FMN) AND ITS SODIUM SALT, AND OF RIBOFLAVIN-4',5'-CYCLOPHOSPHORIC ACID ESTER CHLORIDE AS AN INTERMEDIATE

摘要

Riboflavin-4',5'-cyclo-phosphoric acid ester chloride of the formula I (I), its preparation by reacting an alkali metal salt of riboflavin, in an aprotic solvent, with phosphorus oxychloride, its use for the preparation of riboflavin5'-phosphate and of the sodium salt of riboflavin-5'-phosphate, and a process for the preparation of riboflavin-5'-phosphate or its sodium salt via the novel phosphoric acid ester chloride.