| 摘要 |
<p>An article is provided for delivery of an active ingredient comprising a multiphase construction of a continuous first matrix and a second matrix dispersed therein. The first matrix comprises a thermoplastic material, and the second matrix comprises a thermoplastic material which additionally comprises an active ingredient. The second matrix is a discrete phase of small bodies having size in longest dimension between about 0.05 microns to about 5 mm. The material of the second matrix is selected such that the Rate of Release of the second matrix containing the active ingredient is substantially the same as the Rate of Release of the first matrix and the Tested Physical Property of the multiphase construction is at least about 10 % higher than the Tested Physical Property of a homogeneous combination of equivalent amounts of the first matrix material, the second matrix material and the active agent is at least one the tests selected from the group consisting of the Shear Strength Test, Active Migration Test, the Tensile Modulus Test or the Flexural Modulus Test.</p> |
