PROCESS FOR THE CRYSTALLIZATION FROM WATER OF (S)-N,N'-BIS[2-HYDROXY-1-(HYDROXYMETHYL)ETHYL]-5-[(2-HYDROXY-1-OXOPROPYL)AMINO]-2,4,6-TRIIODO-1,3-BENZENDICARBOXAMIDE

摘要

This invention refers to a process for the crystallization from water of S-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide known as Iopamidol. According to the process of this invention, a crystalline anhydrous Iopamidol in accordance with pharmacopeia standards can be obtained.