摘要 |
<p>The invention relates to novel ureas and urethanes of Formula I: <IMAGE> Formula I which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.</p> |
申请人 |
AMERICAN CYANAMID CO., MADISON, N.J., US |
发明人 |
AYRAL-KALOUSTIAN, SEMIRAMIS, TARRYTOWN, NEW YORK 10951, US;SCHOW, STEVEN R., WASHINGTONVILLE, NEW YORK 10992, US;DU, MILA T., SUFFERN, NEW YORK 10901, US;GIBBONS, JAMES J., JR., WESTWOOD, NEW JERSEY 07675, US |